Trim the silver skin from the tenderloin with a sharp thin knife. Pat completely dry. Season all over with salt, pepper, garlic powder, and smoked paprika.
Heat the olive oil in a large oven-safe skillet over medium-high heat. Sear the tenderloin 2-3 minutes per side until deep golden all over.
Meanwhile, whisk the honey, soy sauce, garlic, vinegar, and ginger in a small bowl.
Reduce heat to medium. Pour the glaze into the skillet with the butter; simmer 1-2 minutes, turning the pork to coat.
Transfer the skillet to a 400°F oven. Roast 12-15 minutes, basting once halfway, until an instant-read thermometer reads 145°F in the thickest part.
Rest 10 minutes under loose foil. Slice into medallions, spoon over the pan glaze, and finish with parsley.